# Efficacy comparison of subcutaneous mastectomy using gasless and gas-insufflation single-port transaxillary approaches for gynecomastia

**Authors:** Yuqing Zhang, Huiling Wang, Jie He, Yaqin Wu, Rui Liu, Xiangyuqin Xiao, Zheng Zeng, Chaojie Zhang

PMC · DOI: 10.3389/fsurg.2025.1562190 · 2025-04-11

## TL;DR

This study compares two surgical techniques for gynecomastia and finds the gasless method is faster without compromising outcomes.

## Contribution

The study introduces a novel comparison of gasless versus gas-insufflation approaches in subcutaneous mastectomy for gynecomastia.

## Key findings

- The gasless approach had significantly shorter surgical times compared to the gas-insufflation method.
- No significant differences were found in bleeding, drainage, hospital stay, or cosmetic outcomes between the two approaches.
- Both methods were clinically feasible and effective for treating gynecomastia without complications.

## Abstract

To evaluate the clinical efficacy of gasless and single-port gas-insufflation transaxillary approaches in subcutaneous mastectomy for treating patients with gynecomastia (GM).

This study enrolled 46 patients with GM from May 2022 to October 2023. Twenty patients underwent subcutaneous mastectomy using the single-port gas-insufflation transaxillary approach (gas-insufflation group), while the other 26 patients received the same procedure through the gasless transaxillary approach (gasless group). This study further conducted inter-group comparisons in terms of the operation time, intraoperative bleeding, volume of postoperative drainage, timing of drainage tube removal, short-term postoperative complications, length of postoperative hospital stay, and medical costs.

All the 46 patients completed the operation successfully without conversion to open surgery, with confirmed diagnosis of GM through pathology. The average surgical time for the gasless group was significantly shorter than that of the gas-insufflation group (38.20 ± 10.773 vs. 62.96 ± 15.311 min, P < 0.01). There were no significant differences between groups in incision length, intraoperative bleeding, unilateral postoperative drainage volume, drainage tube retention time, length of postoperative hospital stay, or postoperative cosmetic outcomes (all P > 0.05).

This study supports the clinical feasibility of using gasless transaxillary approach for subcutaneous mastectomy of patients with GM.

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), mastectomy (MESH:D000072656), GM (MESH:D006177)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12021802/full.md

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Source: https://tomesphere.com/paper/PMC12021802