Fedratinib-Associated Uveitis Effectively Treated With Sub-Tenon's Triamcinolone Acetonide Injection: A Case Report
Akira Saitoh, Ayumi K Saitoh, Erina Daizumoto, Yukiko Nagahara
TL;DR
A 74-year-old woman with myelofibrosis developed uveitis from fedratinib treatment, which was successfully treated with sub-Tenon's triamcinolone acetonide injections.
Contribution
Demonstrates the effectiveness of sub-Tenon's triamcinolone acetonide in treating fedratinib-induced uveitis.
Findings
The patient showed significant improvement in symptoms after receiving sub-Tenon's triamcinolone acetonide injections.
Fedratinib-induced uveitis can be effectively managed with localized corticosteroid treatment.
Subjective and objective symptoms were alleviated within days of the injection.
Abstract
This report describes the case of uveitis in a 74-year-old woman with myelofibrosis who was treated with fedratinib. Both her eyes had hyperemia, anterior chamber cells, keratic precipitates, and vitritis. Based on her clinical history, negative clinical examination findings (except for diabetes), and fedratinib treatment, she was diagnosed with fedratinib-induced uveitis. Subsequently, the patient received sub-Tenon's triamcinolone acetonide (STA) injection in both eyes. The next day, her subjective symptoms were alleviated. Moreover, her objective symptoms were deemed to have improved after the examination performed after a few days. STA injection was extremely effective for treating fedratinib-induced uveitis.
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Taxonomy
TopicsSarcoidosis and Beryllium Toxicity Research · Ocular Diseases and Behçet’s Syndrome · Amyloidosis: Diagnosis, Treatment, Outcomes