Actinomadura welshii sp. nov., a New Mycetoma Agent in Mexico
Lucio Vera-Cabrera, Carmen A. Molina-Torres, Adele E. Crane, Mayra G. Cantú-Alvarez, Mario A. Aguilera-Valenciano, Anabel Gallardo-Rocha, Wendy G. Escalante-Fuentes, Jorge Ocampo-Candiani, Charlotte Avanzi

TL;DR
Scientists discovered a new species of Actinomadura, a bacteria causing mycetoma, in Mexico using DNA sequencing.
Contribution
A new Actinomadura species, Actinomadura welshii, was identified and named through whole-genome sequencing.
Findings
One isolate, LIID-AQ337, was found to belong to a new Actinomadura species.
Whole-genome sequencing revealed a genome of 8,163,638-bp in 22 contigs.
Comparative analysis confirmed the isolate's distinct genomic identity.
Abstract
Actinomadura isolates obtained from seven human mycetoma cases in Mexico were characterized using nucleotide sequence analysis of a portion of the small subunit ribosomal RNA gene. Most isolates were identified as Actinomadura madurae. However, one isolate, LIID-AQ337, showed inconclusive results. To determine its identity, genomic DNA from LIID-AQ337 was subjected to whole-genome sequencing using both short- and long-read sequencing, resulting in a genome of 8,163,638-bp spread in 22 contigs. Comparative analysis against currently available genomes of other Actinomadura species suggested that LIID-AQ337 belongs to a new Actinomadura species. We propose to name it Actinomadura welshii sp. nov in honor of Oliverio Welsh, a Mexican dermatologist dedicated to mycetoma studies in Mexico. Mycetoma is still a neglected infectious disease present in Mexico. The diagnosis and identification of…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsActinomycetales infections and treatment · Mycorrhizal Fungi and Plant Interactions · Phytoplasmas and Hemiptera pathogens
