# PrEP in the key population community: A qualitative study of perspectives on pre-exposure prophylaxis by gay, bisexual and other men who have sex with men and female sex workers in Kigali, Rwanda

**Authors:** Jonathan Ross, Josephine Gasana, Natalia Zotova, Giovanni Ndabakuranye, Fabiola Mabano, Charles Ingabire, Adebola Adedimeji, Gad Murenzi, Viraj V. Patel, Marie A. Brault, Marie A. Brault

PMC · DOI: 10.1371/journal.pgph.0004538 · 2025-04-24

## TL;DR

This study explores how gay and bisexual men and female sex workers in Rwanda perceive and use HIV prevention drugs called PrEP, highlighting the role of community support and the need for discreet access.

## Contribution

The study provides novel insights into PrEP experiences and preferences among GBMSM and FSW in Rwanda, emphasizing community-based strategies to improve HIV prevention.

## Key findings

- Participants emphasized the importance of social networks in providing information and support for PrEP use.
- Stigma and discrimination were common but varied in experience between GBMSM and FSW.
- Community access points for PrEP delivery were suggested as a way to improve engagement and reduce stigma.

## Abstract

Gay, bisexual and other men who have sex with men (GBMSM) and cisgender female sex workers (FSW) are increasingly and disproportionately impacted by HIV in sub-Saharan Africa, yet current PrEP care models in this region are not optimized for these communities. Limited data exist describing experiences and preferences of GBMSM and FSW with respect to accessing and using PrEP. We conducted qualitative, semi-structured interviews with GBMSM and FSW recruited from three health centers and seven community organizations in Kigali, Rwanda. Data were analyzed using a mixed deductive and inductive approach to describe key themes related to initiating and adhering to PrEP. Participants included 18 GBMSM and 14 FSW; 12 were using PrEP at the time of interview, 9 had previously used PrEP, and 11 had never used it. Participants highlighted the central role of their social networks as key sources of information about and support for PrEP use, and described a strong motivation to use PrEP as a way to protect both themselves and their communities from HIV. While stigma and discrimination were pervasive, these were experienced differently by GBMSM and FSW. Participants suggested community access points that allowed more discreet and less frequent contact with health care workers as important and desired strategies to improve engagement. These findings suggest that leveraging community resources for disseminating information about HIV prevention and delivering PrEP could contribute to successful implementation of PrEP for GBMSM and FSW in Rwanda and other settings in SSA.

## Full-text entities

- **Diseases:** discrimination (MESH:D010468)
- **Chemicals:** PrEP (-)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12021139/full.md

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Source: https://tomesphere.com/paper/PMC12021139