# No evidence of positive causal effects of maternal and paternal age at first birth on children’s test scores at age 10 years

**Authors:** Michael Grätz, Felix C. Tropf, Fartein Ask Torvik, Ole A. Andreassen, Torkild H. Lyngstad

PMC · DOI: 10.1038/s41562-025-02108-6 · 2025-02-27

## TL;DR

This study finds no evidence that older maternal or paternal age at first birth improves children's test scores at age 10.

## Contribution

The novel use of Mendelian randomization with polygenic indices provides causal insights into parental age effects on children's education.

## Key findings

- No positive causal effects of maternal age at first birth on children's test scores.
- No positive causal effects of paternal age at first birth on children's test scores.
- Findings contradict sociological theories predicting benefits of older parental age on child education.

## Abstract

Research has shown that higher maternal and paternal age is positively associated with children’s education. Debate continues as to whether these relationships are causal. This is of great interest given the postponement of first births in almost all developed countries during the twentieth century. Here we use an instrumental variable approach (Mendelian randomization) using maternal and paternal polygenic indices (PGIs) for age at first birth—while conditioning on the child’s PGI for age at first birth—to identify the causal effects of maternal and paternal age at first birth on children’s test scores based on data from the Norwegian Mother, Father and Child Cohort study. We do not find evidence of positive causal effects of both maternal and paternal age at first birth on children’s test scores at age 10 years once the children’s PGI and correlations among different PGIs are controlled for. We therefore conclude that our results do not provide evidence in favour of sociological theories that predict positive causal effects of parental age on children’s educational attainment.

Grätz et al. use Mendelian randomization to identify the causal effects of parental age at first birth on children's test scores. They find no causal effects of both maternal and paternal age at first birth on children's test scores at age 10.

## Full-text entities

- **Diseases:** autism (MESH:D001321), psychosis (MESH:D011618), ADHD (MESH:D001289), schizophrenia (MESH:D012559), AFB (MESH:D061219), psychiatric problems (MESH:D001523)
- **Chemicals:** AFB (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12018448/full.md

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Source: https://tomesphere.com/paper/PMC12018448