# Case Report: A rare case of community-acquired Roseomonas mucosa sepsis that presented with persistently normal host-response biomarkers

**Authors:** Xiaomei Xu, Ying Li, Xin Huang

PMC · DOI: 10.3389/fimmu.2025.1521161 · 2025-04-10

## TL;DR

A 59-year-old woman with sepsis caused by Roseomonas mucosa was successfully treated with meropenem despite normal biomarker results.

## Contribution

This case report highlights a rare instance of Roseomonas mucosa sepsis with normal host-response biomarkers.

## Key findings

- Initial metagenomic analysis suggested Pseudomonas aeruginosa, but blood culture identified Roseomonas mucosa.
- The patient was successfully treated with meropenem after antimicrobial susceptibility testing.
- Host-response biomarkers remained negative despite septic shock progression.

## Abstract

Community-acquired Roseomonas mucosa sepsis can lead to significant morbidity and mortality if not diagnosed promptly. We report a case of a 59-year-old woman with community-acquired Roseomonas mucosa sepsis who presented with persistent fever progressing to septic shock, despite repeatedly negative host-response biomarker results. Initial metagenomic analysis of peripheral blood suggested Pseudomonas aeruginosa infection. However, a peripheral blood culture identified Roseomonas mucosa as the causative pathogen. She was cured after switching to meropenem according to blood cultures and antimicrobial susceptibility testing.

## Linked entities

- **Chemicals:** meropenem (PubChem CID 441130)
- **Species:** Roseomonas mucosa (taxon 207340), Pseudomonas aeruginosa (taxon 287)

## Full-text entities

- **Diseases:** Roseomonas mucosa sepsis (MESH:D018805), Pseudomonas aeruginosa infection (MESH:D011552), fever (MESH:D005334), septic shock (MESH:D012772)
- **Chemicals:** meropenem (MESH:D000077731)
- **Species:** Homo sapiens (human, species) [taxon 9606], Roseomonas mucosa (species) [taxon 207340]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12018371/full.md

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Source: https://tomesphere.com/paper/PMC12018371