# Case Image: Cutaneous Leiomyoma

**Authors:** Sunil Jaiswal, Shraddha Uprety, Pratichya Thapa, Prakriti Lamichhane

PMC · DOI: 10.1002/ccr3.70471 · 2025-04-23

## TL;DR

This paper discusses cutaneous leiomyomas, rare benign tumors that can be painful or asymptomatic, and emphasizes the importance of histopathology for diagnosis and HLRCC screening.

## Contribution

The paper highlights the diagnostic importance of histopathology and the need for HLRCC screening in patients with multiple cutaneous leiomyomas.

## Key findings

- Cutaneous leiomyomas are rare benign smooth muscle tumors that can be painful or asymptomatic.
- Histopathology is the gold standard for diagnosis and is essential for identifying Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC).

## Abstract

Cutaneous leiomyomas are rare benign smooth muscle tumors that often present as painful dermal nodules; however, they can be asymptomatic too. Histopathology remains the gold standard for diagnosis and warrants screening for Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) in patients presenting with multiple lesions.

## Linked entities

- **Diseases:** Hereditary Leiomyomatosis and Renal Cell Carcinoma (MONDO:0007888)

## Full-text entities

- **Diseases:** smooth muscle tumors (MESH:D018235), Renal Cell Carcinoma (MESH:D002292), Cutaneous Leiomyoma (MESH:C535516)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12018272/full.md

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Source: https://tomesphere.com/paper/PMC12018272