# Effects of inbound attendees of a mass gathering event on the COVID-19 epidemic using individual-based simulations

**Authors:** Masaya M. Saito, Kotoe Katayama, Akira Naruse, Peiying Ruan, Michio Murakami, Tomoaki Okuda, Tetsuo Ysutaka, Wataru Naito, Masaharu Tsubokura, Seiya Imoto, Ian Christopher N Rocha, Siew Ann Cheong, Siew Ann Cheong, Siew Ann Cheong

PMC · DOI: 10.1371/journal.pone.0321288 · PLOS One · 2025-04-23

## TL;DR

This study uses simulations to show how mass gatherings can be managed to prevent accelerating a COVID-19 outbreak.

## Contribution

A novel individual-based simulation model to assess outbreak control measures at mass gatherings.

## Key findings

- Strict visitor activity restrictions can suppress patient increases similar to event cancellation.
- Slight differences in visitor prevalence compared to residents can be managed with strict controls.
- Simulation scenarios help identify effective containment strategies for mass gatherings.

## Abstract

Given that mass gathering events involve heterogeneous and time-varying contact between residents and visitors, we sought to identify possible measures to prevent the potential acceleration of the outbreak of an emerging infectious disease induced by such events. An individual-based simulator was built based on a description of the reproduction rate among people infected with the infectious disease in a hypothetical city. Three different scenarios were assessed using our simulator, in which controls aimed at reduced contact were assumed to be carried out only in the main event venue or at subsequent additional events, or in which behavior restrictions were carried out among the visitors to the main event. The simulation results indicated that the increase in the number of patients with COVID-19 could possibly be suppressed to a level equivalent to that if the event were not being held so long as the prevalence among visitors was only slightly higher than that among domestic residents and strict requirements were applied to the activities of visitors.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** infectious disease (MESH:D003141), infected (MESH:D007239), COVID-19 (MESH:D000086382)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12017503/full.md

## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12017503/full.md

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Source: https://tomesphere.com/paper/PMC12017503