# Gap of Research to Practice in IC/BPS: A Scientometric Study of Available Evidence

**Authors:** Helia Mostafaei, Hamidreza Ashayeri, Sayeh Afshar, Hadi Mostafaei, Tannaz Aghaei Badr, Hanieh Salehi-pourmehr, Sakineh Hajebrahimi

PMC · DOI: 10.5152/tud.2025.24086 · 2025-04-04

## TL;DR

This study maps the research landscape of interstitial cystitis and bladder pain syndrome to identify gaps between research and clinical practice.

## Contribution

The paper provides a scientometric analysis of IC/BPS research to guide future studies and address current scientific gaps.

## Key findings

- The USA is the most cited country in IC/BPS research, with growing contributions from other nations.
- TZU CHI University is the most active institution in this field, with 154 studies.
- Current research trends focus on genome-wide association and cannabidiols.

## Abstract

Our main objective is to first characterize the current status of the research field of interstitial cystitis and bladder pain syndrome (IC/BPS). This is achieved by mapping, analyzing, and sub-analyzing the field with a scientometric approach, which provides insights into future research. In September 2023, the Scopus database was searched without restrictions on language and date. The following search query was used: Bladder* W/5 pain* W/3 syndrome* AND Interstitial* W/3 (Cystitis* OR Cystides) and the Scopus filters were used to exclude short surveys, book chapters, editorials, notes, and guidelines. The author, journal, institution data, keywords, average citation, countries, and sources were transformed using a Biblioshiny tool (A Shiny app for Bibliometrix), accounting for author spelling, institutional naming, and subgrouping variations. The search strategy yielded 1833 studies. The USA was the most cited country, with other countries showing significant growth in recent years. In terms of affiliations, TZU CHI University was the most relevant in this field (n = 154). The most relevant keywords were “female,” “interstitial cystitis,” “human,” “cystitis interstitial,” “male,” and “cystalgia.” The current topics in IC/BPS research are Genome-wide association and Cannabidiols. By understanding the past, scientific gaps, and the direction of the current research, researchers can aim for their research questions and conduct their research more organized. The scientific gaps of IC/BPS can be effectively understood by paying attention to the models used in this research, which are the results of the systemic analysis of the scientific products in this research field.

## Linked entities

- **Diseases:** Interstitial cystitis (MONDO:0018301), Bladder pain syndrome (MONDO:0018301)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** IC (MESH:C537984), pain (MESH:D010146), bladder pain syndrome (MESH:D018856), Cystitis (MESH:D003556)
- **Chemicals:** Cannabidiols (MESH:D002185)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

16 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12015755/full.md

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Source: https://tomesphere.com/paper/PMC12015755