# Acute arsine poisoning after exposure on cleaning an industrial purifier at a family-run workshop

**Authors:** Hua Zou, Meibian Zhang, Panqi Xue, Fang Wei, Fei Li, Xinglin Fang, Xiaoming Lou, Lifang Zhou

PMC · DOI: 10.3389/fpubh.2025.1542879 · 2025-04-09

## TL;DR

Three workers at a family-run workshop developed acute arsine poisoning after cleaning an industrial purifier, highlighting the need for better occupational health practices.

## Contribution

The study reports a rare case of acute arsine poisoning linked to poor occupational health practices in a family-run workshop.

## Key findings

- Workers showed symptoms like headache, abdominal pain, and hematuria 4–6 hours after exposure.
- High levels of arsenic were found in the purifier's dust and soaking pool water.
- The incident was attributed to a lack of preventive measures against occupational poisoning.

## Abstract

We report a rare incident of acute arsine poisoning when cleaning an industrial purifier to enhance awareness for the prevention of arsine poisoning incidents in the family-run workshop. In this incident, three workers of a family-run cleaning workshop developed symptoms of headache, abdominal pain, chills, fatigue, and hematuria after cleaning an industrial purifier, with a latency period 4–6 h after exposure. Field investigations and laboratory tests were used to investigate the poisoning incident. Red blood cell counts and levels of hemoglobin, alanine transaminase, and urinary arsenic (As) increased, and urinary protein and occult blood tests indicated strongly positive results. The cleaning workshop undertook no effective measures to prevent occupational poisoning. The As concentration in flame retardants, dust on the surface of the industrial purifier, and water in the soaking pool was 269 mg/kg, 1.72 × 105 mg/kg, and 6.89 × 103 mg/L, respectively. This incident highlighted the association of the acute arsine poisoning during the cleaning of an industrial purifier with poor occupational health management practices. Effective measures for the prevention of the acute poisoning should therefore be undertaken.

## Linked entities

- **Chemicals:** arsine (PubChem CID 23969), arsenic (PubChem CID 5359596)

## Full-text entities

- **Diseases:** abdominal pain (MESH:D015746), headache (MESH:D006261), chills (MESH:D023341), fatigue (MESH:D005221), hematuria (MESH:D006417), arsine poisoning (MESH:D011041)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12014608/full.md

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Source: https://tomesphere.com/paper/PMC12014608