# The Pathogenic Potential of Slackia exigua: A Case Study of Bacteremia in a Patient With Oral Infection

**Authors:** Gang Zhou, Lisa Cornelius, Dhammika H. Navarathna

PMC · DOI: 10.1155/crdi/2079663 · 2025-04-15

## TL;DR

This case study reports a rare instance of Slackia exigua bacteremia in a patient with an oral infection and multiple health issues.

## Contribution

The paper highlights the potential pathogenicity of Slackia exigua, which is usually considered nonpathogenic.

## Key findings

- Slackia exigua was identified as the causative agent of bacteremia in a patient with persistent septicemia symptoms.
- The patient recovered after targeted antibiotic therapy and comprehensive dental care.
- The case emphasizes the need for awareness of Slackia exigua's possible role in systemic infections.

## Abstract

Slackia exigua is an anaerobic, Gram-positive, nonspore-forming bacterium that is typically part of the normal oral microbiota. It is generally considered biochemically inert and is often dismissed as a nonpathogenic contaminant in clinical cultures, particularly in respiratory samples. However, in this case study, we report a rare instance of S. exigua bacteremia in a patient with multiple medical comorbidities who was hospitalized after reporting to Emergency Department due to fatigue and right ear pain. The patient subsequently developed signs of persistent symptoms of septicemia, prompting an extensive investigation. Blood cultures identified S. exigua as the causative agent. This case underscores the importance of thorough culture workup and clinical correlation, especially in immunocompromised patients and patients with multiple medical comorbidities. Comprehensive dental care and the administration of targeted antibiotic therapy resulted in the patient's full recovery. This report highlights the potential pathogenic role of S. exigua in certain clinical scenarios and emphasizes the need for awareness of its possible implications in systemic infections.

## Linked entities

- **Species:** Slackia exigua (taxon 84109)

## Full-text entities

- **Diseases:** Oral Infection (MESH:D007239), fatigue (MESH:D005221), ear pain (MESH:D010031), septicemia (MESH:D018805), Bacteremia (MESH:D016470)
- **Species:** Spodoptera exigua (beet armyworm, species) [taxon 7107], Slackia exigua (species) [taxon 84109], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12014268/full.md

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Source: https://tomesphere.com/paper/PMC12014268