# Polymorphous Adenocarcinoma of the Parotid Gland: A Rare Entity in Asians With a Unique Cystic Presentation

**Authors:** Ibadat Preet Kaur, Devendra Pankaj, Meena Santosh, Jitendra Sharan, Neha Singh, Anand Marya

PMC · DOI: 10.1002/ccr3.70441 · Clinical Case Reports · 2025-04-21

## TL;DR

This paper reports a rare case of polymorphous adenocarcinoma in an Indian male that presented as a cystic tumor in the parotid gland.

## Contribution

The novelty lies in the unique cystic presentation of polymorphous adenocarcinoma in an Asian patient, which is rarely reported.

## Key findings

- A 64-year-old Indian male presented with a slow-growing parotid swelling initially diagnosed as cystic.
- Histopathological analysis confirmed it as polymorphous adenocarcinoma, a rare diagnosis in Asian populations.
- The patient remained disease-free for 24 months after surgery.

## Abstract

Polymorphous adenocarcinoma (PAC) of the parotid is a rare entity with minimal reported incidences in the Asian population. It generally presents as a solid tumor and is considered a diagnostic dilemma due to morphological diversity and variable histological patterns. This article reports a unique fluid‐filled PAC of the parotid gland mimicking a cystic lesion in an Indian male, with a review of relevant literature. A 64‐year‐old male patient presented with a slow‐growing swelling of the left parotid region for the last 10 years. The cytology report suggested a cystic swelling. The patient underwent superficial parotidectomy. A detailed histopathological examination confirmed it as a classical variant of PAC. He remains disease‐free over 24 months post‐surgery follow‐up.

## Full-text entities

- **Diseases:** Polymorphous Adenocarcinoma of the Parotid (MESH:D010309), PAC (MESH:D000230), tumor (MESH:D009369), swelling (MESH:D004487)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12011986/full.md

## References

43 references — full list in the complete paper: https://tomesphere.com/paper/PMC12011986/full.md

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Source: https://tomesphere.com/paper/PMC12011986