# A Case of AIDS Diagnosed in the Intensive Care Unit with Concurrent Influenza Infection and Pneumocystis jirovecii Pneumonia

**Authors:** Yeliz Özdemir, İlhan Bahar, Gülfem Ece

PMC · DOI: 10.1155/carm/5588716 · Case Reports in Medicine · 2025-04-14

## TL;DR

This paper presents a case of AIDS diagnosed in an ICU patient with concurrent influenza and Pneumocystis jirovecii pneumonia, emphasizing the importance of early diagnosis and treatment.

## Contribution

The novelty lies in highlighting the co-occurrence of influenza and PCP in a newly diagnosed AIDS patient, emphasizing the need for prompt treatment.

## Key findings

- AIDS patients are at high risk for polymicrobial respiratory infections.
- Early identification and treatment of co-infections improve outcomes.
- Influenza and PCP can coexist in AIDS patients not on ART.

## Abstract

Introduction: People living with HIV (PLWH) are highly susceptible to respiratory infections, particularly pneumonia, which is often polymicrobial. A rapid decline in CD4 T lymphocytes, especially with concurrent influenza, increases the risk of Pneumocystis jirovecii pneumonia (PCP).

Case Presentation: This report discusses a newly diagnosed Acquired Immunodeficiency Syndrome (AIDS) patient with influenza and PCP coinfection, highlighting diagnosis, follow-up, and prognosis.

Conclusions: Community-acquired pneumonia is common in PLWH, especially among those not receiving antiretroviral therapies (ART). Co-infections with bacterial, viral, and fungal pathogens are common. Early identification of etiological agents and prompt treatment are crucial for improving patient outcomes.

## Linked entities

- **Diseases:** AIDS (MONDO:0012268), influenza (MONDO:0005812), Pneumocystis jirovecii pneumonia (MONDO:0019121), pneumonia (MONDO:0005249)

## Full-text entities

- **Genes:** CD4 (CD4 molecule) [NCBI Gene 920] {aka CD4mut, IMD79, Leu-3, OKT4D, T4}
- **Diseases:** PCP (MESH:D011020), PLWH (MESH:C000719191), fungal (MESH:D009181), AIDS (MESH:D000163), Influenza Infection (MESH:D007251), pneumonia (MESH:D011014), HIV (MESH:D015658), respiratory infections (MESH:D012141), Co-infections (MESH:D060085)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12011458/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12011458/full.md

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Source: https://tomesphere.com/paper/PMC12011458