# Perianal Paget's Disease: A Challenge of Surgical Margins in Uncommon Clinical Presentations

## TL;DR

This paper discusses a rare case of perianal Paget's disease that was challenging to surgically treat due to unclear tumor margins.

## Contribution

The novelty lies in highlighting the difficulty of achieving clear surgical margins in perianal Paget's disease coexisting with adenocarcinoma.

## Key findings

- Perianal Paget's disease was found alongside invasive adenocarcinoma of the anus.
- Wide surgical resection failed to achieve clear margins due to ambiguous tumor borders.
- The patient is undergoing topical treatments following surgery.

## Abstract

Perianal Paget's disease is a rare entity that often presents with scaly, erythematous plaques. It manifests with an insidious onset, a high frequency of concurrence with malignancy, and difficulties in ensuring clear resection margins. This case highlights the unexpected findings of perianal Paget's disease when completing an excision of invasive adenocarcinoma of the anus. Due to the difficulty with ambiguous borders, wide resection still had involved margins. The patient is currently completing topical treatments.