# Vaginal candidiasis attributed to hair, skin, and nails supplement: a case report

**Authors:** Faith Whitlock, Akram Al-Makki, Brian Shepler

PMC · DOI: 10.1186/s13256-025-05217-y · Journal of Medical Case Reports · 2025-04-21

## TL;DR

A 64-year-old woman developed a vaginal yeast infection after taking a hair, skin, and nails supplement, suggesting a possible new link.

## Contribution

This is the first documented case linking a hair, skin, and nails supplement to vaginal candidiasis.

## Key findings

- A 64-year-old woman developed vaginal candidiasis after starting a hair, skin, and nails supplement.
- The Naranjo scale indicated a probable association between the supplement and the infection.
- No similar cases were found in the literature, suggesting a novel adverse effect.

## Abstract

This case report presents the first documented instance of vaginal candidiasis linked to the intake of a hair, skin, and nails supplement.

A 64-year-old Caucasian female patient, with a history of chronic kidney disease and multiple comorbidities, developed symptoms of vaginal yeast infection after beginning the supplement. The adverse event was evaluated using the Naranjo Adverse Drug Reaction Probability Scale, scoring a 5, indicating a probable association. Despite extensive literature searches, no similar cases were found, suggesting this might be a unique reaction. This report highlights potential safety concerns with dietary supplements, particularly those not regulated by the Food and Drug Administration, underscoring the need for further investigation into their adverse effects.

The case emphasizes the importance of considering dietary supplements as potential contributors to adverse health events, especially in patients with complex medical histories.

## Linked entities

- **Diseases:** vaginal candidiasis (MONDO:0006014), chronic kidney disease (MONDO:0005300)

## Full-text entities

- **Diseases:** Adverse Drug Reaction (MESH:D064420), yeast infection (MESH:D002181), chronic kidney disease (MESH:D051436), Vaginal candidiasis (MESH:D014627)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12010589/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12010589/full.md

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Source: https://tomesphere.com/paper/PMC12010589