# The Effects of Time‐Restricted Feeding on Handgrip Strength, Vigilance, and Perceived Anxiety and Depression in Older Adults: A Comparative Study Between Active and Sedentary Populations

**Authors:** Mohamed Ali Boujelbane, Khaled Trabelsi, Haitham Jahrami, Achraf Ammar, Atef Salem, Mohamed Kerkeni, Amir Charfi, Omar Boukhris, Cain C. T. Clark, Rabih Roufayel, Nicola Luigi Bragazzi, Wolfgang I. Schöllhorn, Jordan M. Glenn, Hamdi Chtourou

PMC · DOI: 10.1002/hsr2.70692 · Health Science Reports · 2025-04-21

## TL;DR

This study shows that physical activity during Ramadan fasting helps older adults maintain muscle strength and improve mental health more than sedentary individuals.

## Contribution

The study reveals how physical activity can mitigate muscle strength decline and enhance mental health during Ramadan fasting in older adults.

## Key findings

- Both active and sedentary groups improved in vigilance, anxiety, and depression during RIF, with greater benefits in the active group.
- Sedentary participants experienced a decline in handgrip strength, while active individuals maintained muscle strength.
- Regular physical activity during RIF supports physical and mental health in older adults.

## Abstract

Ramadan intermittent fasting (RIF), a form of time‐restricted feeding, influences various physiological and psychological functions. However, its effects on older adults remain insufficiently understood. This study examined the impact of RIF on physical and mental health parameters, comparing active and sedentary older individuals. Specifically, we assessed handgrip strength (HGS), vigilance performance, anxiety, and depression levels to determine whether regular physical activity mitigates potential adverse effects of RIF.

Fifty‐eight older adults (mean age 62.93 ± 3.99 years; 50% female) participated in this study. They were classified into an active group (n = 26) and sedentary group (n = 32) based on self‐reported physical activity levels. Assessments were conducted before and during RIF and included HGS measurement using a handheld dynamometer, a digital psychomotor vigilance test, and validated questionnaires (General Anxiety Disorder‐7, Geriatric Depression Scale, and Physical Activity Scale for the Elderly).

During RIF, both groups showed significant improvements in vigilance, anxiety, and depression scores, with more pronounced benefits in the active group. However, sedentary participants experienced a decline in HGS, whereas active individuals maintained stable muscle strength.

Regular physical activity during RIF appears to enhance vigilance and mental health while preventing muscle strength decline in older adults. These findings highlight the importance of maintaining an active lifestyle during RIF to support both physical and mental health in aging populations.

## Full-text entities

- **Diseases:** Depression (MESH:D003866), Anxiety (MESH:D001007), Anxiety Disorder (MESH:D001008), muscle strength decline (MESH:D009135)

## Full text

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## Figures

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## References

62 references — full list in the complete paper: https://tomesphere.com/paper/PMC12010213/full.md

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Source: https://tomesphere.com/paper/PMC12010213