# Treatment of Facial Asymmetry Caused by Parry-Romberg Syndrome Using Fat Transfer

## TL;DR

This paper discusses using fat transfer to treat facial asymmetry in a rare condition called Parry-Romberg Syndrome.

## Contribution

It presents a unique case of late-onset Parry-Romberg Syndrome treated with fat transfer and highlights its potential as a minimally invasive option.

## Key findings

- Fat transfer improved facial aesthetics in a patient with severe Parry-Romberg Syndrome.
- Some volume loss was observed at the three-month follow-up.
- Personalized treatment strategies are emphasized for managing late-diagnosed cases.

## Abstract

Parry-Romberg syndrome (PRS) is a rare craniofacial disorder marked by progressive unilateral facial atrophy. This case report presents a unique instance of PRS presenting in a 52-year-old female who was diagnosed at age 47 as the syndrome’s usual onset is during the first two decades of life. The patient exhibited severe soft-tissue atrophy on the right side of the face, classified as type 3 PRS, along with associated symptoms such as headaches and a history of depression. The primary aesthetic intervention involved fat transfer (FT) to restore facial symmetry and contour. Postoperative outcomes improved facial aesthetics, though some volume loss was noted at the three-month follow-up. This case highlights the potential of FT as an effective and minimally invasive treatment for severe PRS. It emphasizes the importance of personalized treatment strategies and the need for further research into the long-term management of PRS, particularly in late-diagnosed cases. Further studies are needed to optimize fat grafting techniques and assess long-term outcomes in PRS management.