# A Case Report of COVID-19 With Tracheobronchial Aspergillosis

**Authors:** Haolei Liu, Hailu Jiao, Jun Feng, Hui Gao, Shikui Wu

PMC · DOI: 10.1155/crdi/4627040 · Case Reports in Infectious Diseases · 2025-04-13

## TL;DR

This case report highlights a rare instance of a patient with both COVID-19 and a fungal infection called tracheobronchial aspergillosis, emphasizing the need to consider fungal infections early in the disease.

## Contribution

The novelty lies in documenting a rare co-occurrence of TBA and early-stage COVID-19 without prior immunosuppression.

## Key findings

- A patient with early-stage COVID-19 developed tracheobronchial aspergillosis.
- Combining bronchoscopy, antiviral, and antifungal treatments led to a positive outcome.
- Fungal infections should be considered even in early stages of COVID-19.

## Abstract

The concurrence of COVID-19 and tracheobronchial aspergillosis (TBA) is rarely documented in clinical practice. This report presents a case of TBA in a patient diagnosed with COVID-19 prior to the administration of immunosuppressive agents. This case underscores the necessity of considering fungal infections in patients with COVID-19, even during the early stages of the disease. The combination of timely bronchoscopy, antiviral therapy, and antifungal treatment resulted in favorable therapeutic outcomes for the patient.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** TBA (MESH:C566362), COVID-19 (MESH:D000086382), fungal infections (MESH:D009181)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12009674/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12009674/full.md

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Source: https://tomesphere.com/paper/PMC12009674