# When the Appendix Takes a Detour: A Rare Case of the Appendix Intussuscepting Into the Caecum Mimicking an Appendiceal Mucocele

**Authors:** Ming Chuen Chong, Neil Wu, Abdelhamed Fanta, Osama Shakil, Nasir Z Ahmad

PMC · DOI: 10.7759/cureus.80965 · Cureus · 2025-03-21

## TL;DR

A rare case of appendix intussusception into the caecum was mistaken for a mucocele, requiring surgery for diagnosis and treatment.

## Contribution

This paper presents a rare clinical case of appendix intussusception mimicking an appendiceal mucocele with endometrial histopathology.

## Key findings

- The appendix was found to intussuscept into the caecum during surgery, initially misdiagnosed as a mucocele.
- Histopathological analysis confirmed the presence of appendiceal endometriosis.
- Laparoscopic surgery proved effective for both diagnosis and treatment in this complex case.

## Abstract

Acute appendicitis is a common condition, whereby accurate diagnosis relies on multiple modalities in conjunction with a thorough history and clinical examination. Imaging, particularly computed tomography (CT), is highly sensitive in reliably determining the position of the appendix. It is not unusual for appendicitis to present in atypical ways or be masked as other intra-abdominal conditions, complicating the diagnosis. This report discusses a rare case of intussusception of the appendix into the caecum, with a histopathological specimen later proving the intraoperative specimen as endometrial tissue, highlighting an uncommon presentation. We report the case of a 51-year-old woman who experienced worsening abdominal pain, nausea, and early satiety over several months. Initial evaluation revealed microcytic anaemia and a smoking history of 25 pack-years. Imaging strongly suggested an appendiceal mucocele. A colonoscopy revealed a large caecal polyp originating from within the appendiceal orifice. A multidisciplinary team discussion recommended performing a diagnostic laparoscopy to further guide management. While conducting the laparoscopic surgery, a lump on the taenia coli obscured the view of the appendix, necessitating a partial caecectomy. Postoperative examination of the specimen confirmed intussusception of the appendix into the caecum, later verified by a pathologist to be appendiceal endometriosis. This case highlights the significant diagnostic challenges linked to adult intussusception. Although CT scans and colonoscopy are vital in preoperative assessments, correctly identifying the underlying condition can be difficult. The laparoscopic approach has shown both safety and effectiveness in diagnosis and treatment. Prompt surgical intervention is crucial for resolving intussusception and treating appendicitis to prevent serious complications.

## Linked entities

- **Diseases:** appendicitis (MONDO:0005649), endometriosis (MONDO:0005133)

## Full-text entities

- **Diseases:** abdominal pain (MESH:D015746), Mucocele (MESH:D009078), Acute appendicitis (MESH:D001064), intussusception (MESH:D007443), nausea (MESH:D009325), microcytic anaemia (MESH:D000743), appendiceal endometriosis (MESH:D004715)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12009630/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12009630/full.md

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Source: https://tomesphere.com/paper/PMC12009630