# A Case of Legionella pneumophila With Hearing Loss Improved by Antimicrobial Therapy

**Authors:** Mizuki Takahashi, Kanata Tonosaki, Masashi Noro, Kazuma Ota, Shigeto Oyama

PMC · DOI: 10.7759/cureus.80952 · Cureus · 2025-03-21

## TL;DR

A 59-year-old woman with Legionella pneumophila developed hearing loss, which improved with antibiotic treatment, suggesting a possible link between the infection and hearing issues.

## Contribution

This case report highlights a rare association between Legionella pneumophila infection and sensorineural hearing loss.

## Key findings

- The patient's hearing loss improved alongside pneumonia treatment with pazufloxacin and levofloxacin.
- Sensorineural hearing loss was observed in a patient with L. pneumophila infection.
- The case suggests a potential link between L. pneumophila and hearing loss.

## Abstract

Legionella pneumophila is known to cause various complications, but hearing loss is rarely reported. A 59-year-old woman, healthy by nature, developed a fever and cough and was hospitalized with a diagnosis of L. pneumophila. She had symptoms of hearing loss since admission, and examination revealed bilateral sensorineural hearing loss. However, since this did not interfere with her daily life, she was followed up. After treatment with pazufloxacin and levofloxacin for pneumonia, her hearing loss symptoms improved along with the improvement of her pneumonia. This case suggests that L. pneumophila may be associated with sensorineural hearing loss.

## Linked entities

- **Chemicals:** pazufloxacin (PubChem CID 65957), levofloxacin (PubChem CID 149096)
- **Diseases:** pneumonia (MONDO:0005249), sensorineural hearing loss (MONDO:0010576)
- **Species:** Legionella pneumophila (taxon 446)

## Full-text entities

- **Diseases:** pneumonia (MESH:D011014), sensorineural hearing loss (MESH:D006319), Hearing Loss (MESH:D034381), cough (MESH:D003371), fever (MESH:D005334)
- **Species:** Homo sapiens (human, species) [taxon 9606], Legionella pneumophila (species) [taxon 446]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12009593/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12009593/full.md

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Source: https://tomesphere.com/paper/PMC12009593