# Deceptive Pseudotuberculous Presentation of a Pulmonary Lepidic Adenocarcinoma

**Authors:** Rachid Benchanna, Mohamed Kaakoua, Mohamed Amine Azami, Salah Bellasri, Hicham Janah, Anas Kherrab, Soufiane Sassi, Amine Benjelloune

PMC · DOI: 10.7759/cureus.80947 · Cureus · 2025-03-21

## TL;DR

A case of lung cancer mistaken for tuberculosis highlights the importance of considering rare cancer types in chronic lung conditions.

## Contribution

The paper presents a rare case of lepidic adenocarcinoma mimicking tuberculosis, emphasizing diagnostic challenges and the need for broader awareness.

## Key findings

- The tumor showed no EGFR expression or ALK rearrangement.
- The case involved bilateral pulmonary involvement without distant metastases.
- The authors stress the importance of considering lepidic ADC in chronic lung consolidations.

## Abstract

Misleading presentations of lepidic adenocarcinomas (ADC) often lead to diagnostic delays, potentially reducing the chances of curative treatment. We report a case of mucinous lepidic ADC that mimicked pulmonary tuberculosis and was diagnosed at a late stage. The tumor showed no epidermal growth factor receptor (EGFR) expression or anaplastic lymphoma kinase (ALK) rearrangement and was characterized by bilateral pulmonary involvement without distant metastases. Through this case, the authors emphasize the need to consider lepidic ADC in cases of chronic pulmonary consolidation, despite atypical radio-clinical presentations that may be encountered in routine practice.

## Linked entities

- **Genes:** EGFR (epidermal growth factor receptor) [NCBI Gene 1956], ALK (ALK receptor tyrosine kinase) [NCBI Gene 238]
- **Diseases:** pulmonary tuberculosis (MONDO:0006052)

## Full-text entities

- **Genes:** EGFR (epidermal growth factor receptor) [NCBI Gene 1956] {aka ERBB, ERBB1, ERRP, HER1, NISBD2, NNCIS}, ALK (ALK receptor tyrosine kinase) [NCBI Gene 238] {aka ALK1, CD246, NBLST3}
- **Diseases:** chronic pulmonary consolidation (MESH:D055370), tumor (MESH:D009369), metastases (MESH:D009362), ADC (MESH:D000230), pulmonary tuberculosis (MESH:D014397), mucinous (MESH:D002288)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12009554/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12009554/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12009554/full.md

---
Source: https://tomesphere.com/paper/PMC12009554