# Heterotopic pancreatic tissue presenting as an unusual cause of gastric outlet obstruction in infancy: a case report

**Authors:** Ahmed Oshiba, Karim Darweesh, Hend Sharafeldin, Mostafa Kotb

PMC · DOI: 10.1186/s13256-024-04941-1 · Journal of Medical Case Reports · 2025-04-18

## TL;DR

A 2-month-old girl had repeated vomiting due to a rare condition where pancreatic tissue blocked her stomach's outlet, requiring surgery for removal.

## Contribution

This case report highlights heterotopic pancreatic tissue as a rare cause of gastric outlet obstruction in infants.

## Key findings

- A 2-month-old girl had gastric outlet obstruction caused by ectopic pancreatic tissue.
- Surgical removal of the mass resolved the obstruction, confirmed by pathological analysis.
- Histology is essential for definitive diagnosis despite initial imaging results.

## Abstract

Gastric outlet obstruction beyond the neonatal period is an extremely rare condition when other causes such as infantile hypertrophic pyloric stenosis, pyloric atresia, and antral diaphragm are ruled out. Herein, we present the case of a 2-month-old girl who presented with repeated nonbilious vomiting and showed ectopic pancreatic tissue compressing the pylorus of the stomach.

A 2-month-old Caucasian girl who suffered from frequent attacks of projectile vomiting that was not resolved by medication presented to our institute. On ultrasonography, pyloric stenosis was excluded, while on gastrograffin study, there was a hugely dilated stomach with delayed passage of contrast to the distal bowel. On surgical exploration, there was an exophytic pyloric mass compressing the pyloric canal, which was completely excised. Pathological results confirmed the presence of heterotopic pancreatic tissue.

Heterotopic pancreas should always be considered as one of the rare differentials of the causes of gastric outlet obstruction in infants. Although many investigations such as sonogram and upper gastrointestinal series help in diagnosis, histology remains the definitive test in reaching the final diagnosis.

## Linked entities

- **Diseases:** gastric outlet obstruction (MONDO:0001561), infantile hypertrophic pyloric stenosis (MONDO:0001560), pyloric atresia (MONDO:0009944)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** pyloric atresia (MESH:C562561), ectopic pancreatic tissue (MESH:D002828), Gastric outlet obstruction (MESH:D017219), hypertrophic pyloric stenosis (MESH:D046248), vomiting (MESH:D014839), pyloric stenosis (MESH:D011707)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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Source: https://tomesphere.com/paper/PMC12008855