# Synchronous breast carcinoma with ipsilateral axillary tuberculosis, posing a diagnostic dilemma

**Authors:** Felix A Raj, Imran T Ajmal, Amrithraj Thiyagarajan, M Y Ajmal, Pavithra Selvam, Venkiteswaran Muralidhar

PMC · DOI: 10.1093/jscr/rjaf218 · Journal of Surgical Case Reports · 2025-04-19

## TL;DR

A 63-year-old woman had breast cancer and tuberculosis in the same armpit, requiring careful diagnosis and combined treatment.

## Contribution

Highlights the rare coexistence of breast cancer and axillary tuberculosis, emphasizing the need for accurate histopathological diagnosis.

## Key findings

- Patient had synchronous breast cancer and TB in the same axilla.
- Histopathology was crucial for distinguishing between the two conditions.
- Combined treatment led to complete disease resolution.

## Abstract

This case report describes a 63-year-old postmenopausal diabetic female with synchronous primary invasive ductal carcinoma of the right breast and tuberculosis (TB) of the ipsilateral axillary lymph nodes. Presenting with a palpable right breast lump and axillary lymphadenopathy, the patient underwent imaging, revealing BIRADS V classification and suspicious lymph nodes. Core needle biopsy confirmed invasive carcinoma, while lymph node histology revealed caseating granulomatous inflammation consistent with TB. Managed with modified radical mastectomy, adjuvant chemotherapy, and antitubercular therapy, the patient showed complete disease resolution on follow-up. This rare coexistence underscores the necessity for histopathological confirmation and multidisciplinary management to optimize outcomes.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), breast carcinoma (MONDO:0004989), tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** granulomatous inflammation (MESH:D007249), TB (MESH:D014376), invasive ductal carcinoma (MESH:D044584), lymphadenopathy (MESH:D008206), carcinoma (MESH:D009369), diabetic (MESH:D003920), breast carcinoma (MESH:D001943)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12008117/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12008117/full.md

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Source: https://tomesphere.com/paper/PMC12008117