# Adenoid cystic carcinoma in a male breast: a case report and literature review

**Authors:** Vatsala Kapoor, Cara Moses, Sarah P Hanna, John W Odom

PMC · DOI: 10.1093/jscr/rjaf226 · Journal of Surgical Case Reports · 2025-04-19

## TL;DR

A rare case of adenoid cystic carcinoma in a male breast is reported, highlighting the challenges in diagnosis and treatment due to its rarity.

## Contribution

This case report adds to the limited literature on male breast adenoid cystic carcinoma and emphasizes the need for careful diagnostic evaluation.

## Key findings

- A 63-year-old male was diagnosed with adenoid cystic carcinoma of the breast after initial suspicion of inflammatory breast cancer.
- The patient underwent modified radical mastectomy and remains disease-free without adjuvant therapy.
- The case underscores the diagnostic challenges and lack of treatment guidelines for this rare cancer subtype.

## Abstract

Breast adenoid cystic carcinoma (BACC) is a rare occurrence constituting less than 0.1% of primary breast cancers. BACC is even more rare in male patients. Furthermore, there are currently no concrete treatment guidelines for BACC. Therefore, it is imperative to conduct a thoughtful evaluation and diagnostic workup when a potential case is encountered. We report a 63-year old male who initially presented to the dermatologist with a nonhealing inflamed leiomyoma of the left breast, raising suspicion for inflammatory breast cancer. A percutaneous biopsy was performed, and pathology revealed fragments of cribriform and papillary-like carcinoma, leading to a differential diagnosis including adenoid cystic carcinoma and basal-like ductal carcinoma in situ. A modified radical mastectomy was performed, and final surgical pathology revealed BACC. The patient did not receive any adjuvant therapy and is currently without any evidence of disease.

## Linked entities

- **Diseases:** adenoid cystic carcinoma (MONDO:0004971), inflammatory breast cancer (MONDO:0006804), leiomyoma (MONDO:0001572)

## Full-text entities

- **Diseases:** basal-like ductal carcinoma in situ (MESH:D002285), breast cancers (MESH:D001943), inflammatory breast cancer (MESH:D058922), papillary-like carcinoma (MESH:D002291), BACC (MESH:D005348), Adenoid cystic carcinoma (MESH:D003528), leiomyoma (MESH:D007889)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12008116/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12008116/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12008116/full.md

---
Source: https://tomesphere.com/paper/PMC12008116