# Disseminated Superficial Actinic Porokeratosis in a Mother and Daughter: A Case Report

## TL;DR

A mother and daughter with a rare skin condition called disseminated superficial actinic porokeratosis showed improvement with treatment.

## Contribution

This case report highlights a rare familial occurrence of DSAP and demonstrates successful treatment with isotretinoin and keratolytics.

## Key findings

- A mother and daughter presented with similar symptoms of DSAP, indicating possible familial transmission.
- Treatment with oral isotretinoin and topical keratolytics led to significant improvement within 1.5 months.
- Early diagnosis and management of DSAP may reduce the risk of malignancy.

## Abstract

Porokeratosis is an autosomal dominant condition of epidermal keratinization. There are many clinical and morphological variants of porokeratosis, the most prevalent of which is disseminated superficial actinic porokeratosis (DSAP), which commonly affects photoexposed areas. Here, we present a 52-year-old woman and her 24-year-old daughter having similar complaints of gradually enlarging, annular hyperpigmented plaques on photoexposed areas suggesting familial transmission. Diagnosed as DSAP, treatment with oral isotretinoin and topical keratolytics showed significant improvement within one and a half months. This case report highlights familial DSAP cases in a mother and daughter, which is rare, emphasizing the importance of early diagnosis and management for better outcomes and reduced malignancy risk.