# Clinical Utility of Polymerase Chain Reaction (PCR) in Diagnosing and Managing Bacterial Infections: A Case Series of Three Patients With Acinetobacter baumannii

**Authors:** Jalal Ibrahim, Riley J Stone, Torrin Jacobsen, Robert Norman

PMC · DOI: 10.7759/cureus.80823 · Cureus · 2025-03-19

## TL;DR

This paper shows how PCR helps diagnose and treat bacterial infections faster and more accurately than traditional methods, using three patient cases.

## Contribution

The paper demonstrates PCR's clinical utility in managing Acinetobacter baumannii infections through real-world case examples.

## Key findings

- PCR provided rapid and accurate diagnosis of Acinetobacter baumannii in three patients.
- PCR outperformed traditional culture methods in speed and precision.
- Using PCR reduced the need for broad-spectrum antibiotics and lowered healthcare costs.

## Abstract

This case series highlights the critical role of polymerase chain reaction (PCR) in diagnosing and managing bacterial infections in dermatology. We present three cases of patients with the same bacterial infection, identified through PCR, and discuss the implications for treatment. The series highlights the advantages of PCR over traditional culture methods, emphasizing its ability to deliver rapid, accurate diagnoses and facilitate targeted therapeutic interventions. Unlike cultures, which can be time-consuming, PCR provides a quicker and more precise identification of pathogens. Additionally, we outline the cost-saving potential of PCR, as its efficiency in pinpointing infections can reduce the need for broad-spectrum antibiotics, minimize unnecessary diagnostic procedures, and shorten the duration of patient illness, thereby contributing to overall healthcare savings.

## Full-text entities

- **Diseases:** Bacterial Infections (MESH:D001424), infections (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606], Acinetobacter baumannii (species) [taxon 470]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12007438/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12007438/full.md

---
Source: https://tomesphere.com/paper/PMC12007438