# Revision of medial unicompartmental knee arthroplasty—Not as uncomplicated as one thought? Analysis of survival and re‐revisions from a single centre

**Authors:** Sebastian Bockholt, Georg Gosheger, Burkhard Moellenbeck, Kristian Nikolaus Schneider, Jan Schwarze, Christoph Theil

PMC · DOI: 10.1002/jeo2.70250 · Journal of Experimental Orthopaedics · 2025-04-18

## TL;DR

This study examines the outcomes of revising a type of knee surgery called medial unicompartmental knee arthroplasty, finding that many patients need further revisions due to implant failure.

## Contribution

The study provides survival data and identifies reasons for re-revisions after revision total knee arthroplasty following failed unicompartmental knee arthroplasty.

## Key findings

- Revisions of medial unicompartmental knee arthroplasty often require complex implants.
- A significant proportion of patients undergo re-revision due to tibial loosening and infection.
- Rotating hinge implants showed reduced survival rates compared to other designs.

## Abstract

Medial unicompartmental knee arthroplasty (UKA) is a treatment option for medial knee osteoarthritis, with an increase in surgeries over the last few years. However, the results of revision total knee arthroplasty (TKA) after a UKA vary greatly. The purpose of the study was to examine the survival after revision TKA of a failed UKA.

This is a retrospective single‐centre analysis that includes 35 revision TKA procedures after the failed UKA performed from 2004 to 2019. The median follow‐up after revision TKA was 39 months (interquartile range [IQR]: 32–52). The indication for revision of the UKA was aseptic loosening in 49% of patients (17/35). We evaluated demographic factors, reason for revision and revision implant used with descriptive statistics. Implant survival analysis with a focus on re‐revision‐free survival and potential re‐revisions was performed using Kaplan–Meier survival curves. Differences in survival were analyzed using the log‐rank test. p Value was set at 0.05.

Forty per cent (14/35) of revision implants were posterior stabilized revision TKA, followed by 34% (12/35) of condylar constrained designs and 23% of rotating hinged TKA (8/35). Only one patient was revised to a cruciate retaining primary implant (3%). The re‐revision‐free survival after revision TKA amounted to 94% (95% confidence interval [CI]: 91%–100%) after 1 year, 80% (95% CI: 67%–93%) after 2 years and 74% (95% CI: 56%–90%) at 5 years. Twenty‐three per cent of patients (8/35) underwent re‐revision after the initial UKA revision after a median time period of 21 months (IQR: 12–24). The reasons for repeat revision were tibial aseptic loosening in 9% of patients (3/35), periprosthetic joint infection (PJI) in 9% of patients (3/35) and instability in 5% (2/35). Rotating hinge knee implants showed reduced survivorship.

Revision of medial UKA is associated with an increased use of more elaborate and complex revision implants. There is a substantial risk of repeat revision, with aseptic tibial loosening and PJI being the main reasons for the failure of this series.

Level III.

## Linked entities

- **Diseases:** osteoarthritis (MONDO:0005178), periprosthetic joint infection (MONDO:0800179)

## Full-text entities

- **Diseases:** medial knee osteoarthritis (MESH:D020370), instability (MESH:D043171), PJI (MESH:D057068), aseptic loosening (MESH:D011475)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12007015/full.md

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Source: https://tomesphere.com/paper/PMC12007015