# Myeloid sarcoma of the heart—A clinicopathological correlation

## TL;DR

A rare case of myeloid sarcoma in the heart is described, leading to heart failure and death despite prior leukemia treatment.

## Contribution

This paper presents a rare clinical case of myeloid sarcoma of the heart with clinicopathological insights.

## Key findings

- The patient exhibited signs of infiltrative cardiomyopathy due to heart infiltration by myeloid sarcoma.
- Autopsy confirmed the presence of myeloid sarcoma in the heart, contributing to fatal cardiogenic shock.

## Abstract

A 63-year-old woman with a history of acute myeloid leukemia followed by stem cell transplantation presented with acute heart failure. Transthoracic echocardiography revealed a preserved left ventricular ejection fraction with severe ventricular hypertrophy and signs of elevated filling pressures indicating infiltrative cardiomyopathy. She died from cardiac arrest due to cardiogenic shock. The autopsy revealed an enlarged heart with a fish-flesh appearance. Here, we describe a rare case of a myeloid sarcoma of the heart.