Acute Intoxication With Poison Hemlock (Conium maculatum)
João Nunes, Sergio Pina, Ana Carolina Oliveira, Javier Moreno, Pilar Pérez

TL;DR
Poison hemlock is highly toxic and can be mistaken for edible plants, but with quick diagnosis and treatment, recovery is possible.
Contribution
The paper presents two cases of poison hemlock intoxication with different severity levels and successful recovery outcomes.
Findings
Poison hemlock intoxication can mimic nicotine effects on the nervous system.
Rapid diagnosis and medical intervention are crucial for recovery from poisoning.
Two cases of intoxication with full recovery were successfully treated in Portugal.
Abstract
Poison hemlock (Conium maculatum) is regarded as one of the most poisonous plants worldwide, and it can easily be misidentified as edible species as celery, parsnip (for their leaves), or carrots (for their roots). Toxicity comes from piperidine alkaloids, which mimic nicotine effect on the autonomous nervous system giving a clinical picture of nicotinic syndrome with an initial excitatory phase and secondary inhibitory one. In Portugal, this plant is used as an ancient technique for river fishing. Death comes from respiratory arrest and hemodynamic collapse; rapid diagnosis and medical support are essential for successful treatment. We present two cases of different degrees of intoxication with total recovery.
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Taxonomy
TopicsPlant-based Medicinal Research · Poisoning and overdose treatments · Chemical synthesis and alkaloids
