# Bilateral Polycystic Kidney Disease and Inferior Vena Cava (IVC) Thrombosis: A Cadaveric Study

**Authors:** Gongchao Yang, Morgan E Schock, Peyton W Wall, Yuefeng Lu, Dongmei Cui

PMC · DOI: 10.7759/cureus.80765 · 2025-03-18

## TL;DR

This cadaveric study reports a rare case of bilateral polycystic kidney disease with liver cysts and inferior vena cava thrombosis in a 90-year-old male.

## Contribution

The study presents a rare anatomical case linking bilateral polycystic kidney disease with liver cysts and IVC thrombosis.

## Key findings

- The cadaver had enlarged kidneys with multiple cysts and partial absence of renal capsules.
- A polycystic liver and an inferior vena cava filter were found, indicating a history of venous thrombosis.
- The left kidney had notably larger cysts compared to the right.

## Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disease and one of the most common causes of end-stage kidney disease. The occurrence of bilateral polycystic kidney disease with liver cysts is uncommon. A case of bilateral polycystic kidney disease, found to have liver cysts and inferior vena cava thrombosis in a cadaveric study, is presented in this study. Dissection was performed on a 90-year-old Caucasian male cadaver. Both kidneys were enlarged and contained multiple cysts with normal renal tissue interposed. When comparing the two kidneys, the cysts on the left were notably larger. There was a partial absence of renal capsules. Additionally, a polycystic liver and an inferior vena cava filter were found during the dissection. The patient's history of venous thrombosis is indicated by the previously inserted inferior vena cava filter.

## Linked entities

- **Diseases:** Autosomal dominant polycystic kidney disease (MONDO:0004691), end-stage kidney disease (MONDO:0004375)

## Full-text entities

- **Diseases:** Inferior Vena Cava (IVC) Thrombosis (MESH:C563013), ADPKD (MESH:D016891), cysts (MESH:D003560), genetic kidney disease (MESH:D007674), venous thrombosis (MESH:D020246), liver cysts (MESH:D017093), polycystic liver (MESH:C536330), end-stage kidney disease (MESH:D007676), Polycystic Kidney Disease (MESH:D007690)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12004418/full.md

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Source: https://tomesphere.com/paper/PMC12004418