# Primary aorto‐enteric fistula diagnosed by double‐balloon endoscopy

**Authors:** Momoko Yamamoto, Kei Nomura, Tomoyoshi Shibuya, Masashi Omori, Rina Odakura, Kentaro Ito, Hirofumi Fukushima, Osamu Nomura, Dai Ishikawa, Akihito Nagahara

PMC · DOI: 10.1002/deo2.70118 · DEN Open · 2025-04-16

## TL;DR

A rare case of primary aorto-enteric fistula was diagnosed using double-balloon endoscopy in an elderly patient with gastrointestinal bleeding.

## Contribution

Highlights the diagnostic value of double-balloon endoscopy in identifying PAEF when standard endoscopies fail.

## Key findings

- Double-balloon endoscopy revealed a submucosal tumor-like lesion in the jejunum, leading to suspicion of PAEF.
- Computed tomography confirmed free air near an abdominal aortic aneurysm, confirming the diagnosis of PAEF.
- Successful treatment with a stent graft and laparotomy showed no recurrence postoperatively.

## Abstract

A primary aorto‐enteric fistula (PAEF), rarer than a secondary aorto‐enteric fistula, is a direct rupture of the bowel by an abdominal aortic aneurysm (AAA). More than 54% of cases were in the duodenum, while jejunum and ileum were affected in only 15% of cases.

An 82‐year‐old woman with hematemesis and hematochezia was admitted to our hospital emergently. Upper and lower endoscopies did not reveal the source of bleeding. We performed an urgent antegrade double‐balloon endoscopy, revealing a submucosal tumor‐like protuberance with an ulcer in the jejunum. These findings raised suspicion by PAEF. Subsequent computed tomography showed free air near the AAA, confirming PAEF as the hemorrhage source. An abdominal aortic stent graft was implanted, followed by laparotomy. An adhesion between the AAA and small intestinal wall was found. Postoperative recovery was uneventful, with no recurrence observed. This case underscores the importance of considering PAEF as a potential diagnosis in patients with gastrointestinal bleeding and a history of AAA. Endoscopists should be aware of submucosal tumor such as in this case to avoid misdiagnosing PAEF, as diagnosis and intervention are crucial for favorable outcomes.

## Linked entities

- **Diseases:** abdominal aortic aneurysm (MONDO:0005350)

## Full-text entities

- **Diseases:** gastrointestinal bleeding (MESH:D006471), submucosal tumor (MESH:D009369), AAA (MESH:D017544), rupture (MESH:D012421), bleeding (MESH:D006470), bowel (MESH:D012778), PAEF (MESH:D004751), hematemesis (MESH:D006396), ulcer (MESH:D014456)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12003205/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12003205/full.md

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Source: https://tomesphere.com/paper/PMC12003205