# Neurosyphilis: An Uncommon Diagnosis in the Antibiotic Era

## TL;DR

This paper discusses a rare case of neurosyphilis, highlighting its challenging diagnosis due to its uncommon presentation in the modern antibiotic era.

## Contribution

The paper presents a unique clinical case of neurosyphilis with acute confusion and agitation, emphasizing the need for awareness of this rare condition.

## Key findings

- Neurosyphilis can present with acute confusion and agitation, mimicking other neurological conditions.
- The case underscores the importance of considering neurosyphilis in differential diagnoses despite its rarity.
- Early diagnosis and treatment are critical to prevent severe neurological complications.

## Abstract

Neurosyphilis results from infection of the nervous system by Treponema pallidum. The diagnosis of neurosyphilis is overlooked because of its rarity. It can manifest as early or late symptoms after primary infection with syphilis, with symptoms lying on the spectrum of asymptomatic early neurosyphilis, syphilitic meningitis, meningovascular syphilis, general paresis, and tabes dorsalis. In this report, we present a case of neurosyphilis presenting with acute confusion and agitation.