# An Exophytic Pancreatic Mass Diagnosed as Ganglioneuroma

**Authors:** Jinye Liu, Abdulazeez Swaiti, Saeed Graham, Alessandra Martorella, Sha Yi, Kim Geisinger, Zarak Hassan Khan, Kara Regan

PMC · DOI: 10.14309/crj.0000000000001677 · ACG Case Reports Journal · 2025-04-16

## TL;DR

A rare case of a pancreatic ganglioneuroma tumor is diagnosed in a 47-year-old man through endoscopic ultrasound and biopsy.

## Contribution

This case report highlights the diagnosis of a rare neuroendocrine tumor in an unusual location.

## Key findings

- A ganglioneuroma was diagnosed in the pancreas of a 47-year-old man.
- The tumor was confirmed via endoscopic ultrasound and fine-needle biopsy.
- The tumor was exophytic and inseparable from the pancreatic body.

## Abstract

Ganglioneuromas are rare neuroendocrine tumors affecting around one in a million, mostly young adults. These slow-growing, well-differentiated neuroepithelial tumors originate from the neural crest and involve the sympathetic nervous system. We present an unusual case of a 47-year-old African American man with mildly elevated liver enzymes who was incidentally found to have a suspected pancreatic mass. Endoscopic ultrasound and fine-needle biopsies confirmed the diagnosis of a ganglioneuroma, inseparable and exophytic in the body of the pancreas extending into the tail.

## Linked entities

- **Diseases:** ganglioneuroma (MONDO:0005033)

## Full-text entities

- **Diseases:** Pancreatic Mass (MESH:D010195), Ganglioneuroma (MESH:D005729), neuroepithelial tumors (MESH:D018302), neuroendocrine tumors (MESH:D018358)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12002381/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12002381/full.md

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Source: https://tomesphere.com/paper/PMC12002381