# A systematic review and meta-analysis of the traumatogenic phenotype hypothesis of psychosis: commentary, Alameda

**Authors:** Luis Alameda

PMC · DOI: 10.1192/bjo.2024.863 · BJPsych Open · 2025-03-03

## TL;DR

This paper reviews how childhood trauma affects the clinical profile of psychosis, focusing on abuse and neglect.

## Contribution

The paper provides a meta-analytical commentary on the role of childhood trauma in shaping psychosis profiles.

## Key findings

- Childhood trauma, especially abuse and neglect, influences the clinical profile of psychosis.
- Selective evidence from stringent studies limits understanding of trauma's differential roles.

## Abstract

Onyeama et al have examined the clinical profile of individuals with psychosis and childhood trauma using a stringent approach that yielded selective evidence, affecting power and insight into the specific and differential roles of abuse and neglect in the clinical profile. This commentary puts the findings into a broader meta-analytical context.

## Linked entities

- **Diseases:** psychosis (MONDO:0005485)

## Full-text entities

- **Diseases:** abuse and neglect (MESH:D058069), psychosis (MESH:D011618), trauma (MESH:D014947)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12001925/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12001925/full.md

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Source: https://tomesphere.com/paper/PMC12001925