# Lyme Carditis With Complete Heart Block

**Authors:** Ashot Batikyan, Hakob Harutyunyan, Vahagn Tamazyan, Aleksan Khachatryan, Pavel Abalyan, Pawel Borkowski

PMC · DOI: 10.7759/cureus.80724 · Cureus · 2025-03-17

## TL;DR

A 42-year-old man with Lyme carditis developed a severe heart block but improved rapidly with ceftriaxone treatment.

## Contribution

This case highlights the importance of early diagnosis and treatment of Lyme carditis to avoid serious complications.

## Key findings

- Third-degree AV block resolved within 48 hours with intravenous ceftriaxone.
- Transition from third-degree to first-degree AV block occurred after treatment initiation.
- Early recognition prevented the need for permanent pacemaker implantation.

## Abstract

Lyme disease, the most common tick-borne infection in North America, can lead to multi-organ involvement, including Lyme carditis. This report describes the case of a 42-year-old male who presented with a third-degree atrioventricular (AV) block due to Lyme carditis. The patient reported a history of a recent tick bite and erythema migrans rash, followed by progressive fatigue, palpitations, and dyspnea. Initial electrocardiogram (EKG) revealed third-degree AV block with ventricular escape rhythm, necessitating temporary transvenous pacing and intravenous ceftriaxone therapy. Within 48 hours, the patient significantly improved, transitioning to first-degree AV block with a decreasing PR interval. After clinical stabilization, intravenous ceftriaxone was switched to oral doxycycline, and the patient was discharged with outpatient follow-up. This case emphasizes the significance of early recognition and treatment of Lyme carditis to prevent life-threatening complications and avoid unnecessary permanent pacemaker implantation.

## Linked entities

- **Chemicals:** ceftriaxone (PubChem CID 5479530), doxycycline (PubChem CID 54671203)
- **Diseases:** Lyme disease (MONDO:0019632)

## Full-text entities

- **Diseases:** palpitations (MESH:D006331), AV block (MESH:D054537), fatigue (MESH:D005221), tick (MESH:D013985), Lyme Carditis (MESH:D009205), dyspnea (MESH:D004417), Heart Block (MESH:D006327), tick-borne infection (MESH:D017282), erythema migrans rash (MESH:D005929), Lyme disease (MESH:D008193)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12001294/full.md

## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC12001294/full.md

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Source: https://tomesphere.com/paper/PMC12001294