# A Case Report of Drug‐Induced Hemorrhagic Bullae

## TL;DR

This paper reports a rare skin reaction caused by two drugs, vancomycin and alteplase, and highlights the need for proper medical action.

## Contribution

The novelty lies in reporting hemorrhagic bullae caused by vancomycin and alteplase, which is a rare and previously underreported drug-induced adverse reaction.

## Key findings

- Vancomycin and alteplase can cause hemorrhagic bullae as a rare adverse reaction.
- Physicians should be cautious and take appropriate action when encountering such reactions.

## Abstract

Hemorrhagic bullae is a rare, non‐immune, cutaneous adverse reaction that happens after the administration of some medicine. This case is a unique report of vancomycin and alteplase‐induced hemorrhagic bullae and warns physicians and healthcare teams to take action properly.