# A New Form of Combined Hyperactive Dysfunction Syndrome: A Unique Case

## TL;DR

This paper describes a rare case of a young woman with combined hyperactive dysfunction syndrome involving multiple cranial nerves.

## Contribution

The novelty lies in documenting a rare simultaneous occurrence of trigeminal, occipital, and glossopharyngeal neuralgia in one patient.

## Key findings

- A young woman exhibited symptoms of trigeminal, occipital, and glossopharyngeal neuralgia simultaneously.
- This case highlights the rare association of overactivity in multiple cranial nerves.
- Such combined hyperactive dysfunction syndrome is extremely uncommon in clinical practice.

## Abstract

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. There are different types of pain. Neuropathic pain is caused by a lesion or pathological condition of the somatosensory nervous system. One of the most well-known neuropathic pains is trigeminal neuralgia (TN). However, occipital neuralgia (ON) and glossopharyngeal neuralgia (GPN) exist. These three rare pathologies occur in a very small part of the global population. Combined hyperactive dysfunction syndrome is a rare disorder characterized by overactivity in different cranial nerves, TN, hemifacial spasm, and GPN. In this paper, we present a very rare case of a young woman affected by an association of overactivity in the trigeminal, occipital, and glossopharyngeal nerves, leading to TN, ON, and GPN simultaneously.