# Triangular Lunulae in Papillon–Lefèvre Syndrome: A Case Report

**Authors:** Zarak Khan Shiraz, Fahad Faizullah, Qaisar Ali Khan, Irfan Ullah, Mehran Khan, Bader Semakieh, Zain Ul Islam, Ravina Verma

PMC · DOI: 10.1002/ccr3.70339 · Clinical Case Reports · 2025-04-14

## TL;DR

This case report shows triangular lunulae in a rare genetic syndrome, highlighting the importance of early diagnosis and awareness of consanguinity.

## Contribution

The paper reports triangular lunulae in Papillon–Lefèvre syndrome, expanding their association beyond Nail–Patella Syndrome.

## Key findings

- Triangular lunulae can appear in Papillon–Lefèvre syndrome, not just Nail–Patella Syndrome.
- Early diagnosis and treatment can reduce morbidity in Papillon–Lefèvre syndrome.
- Raising awareness about consanguinity may help reduce the disease's impact in affected populations.

## Abstract

Triangular lunulae, typically associated with Nail–Patella Syndrome, may also present in other syndromes, as seen in this case. Papillon–Lefèvre syndrome is a rare genodermatosis linked to significant morbidity. Consanguinity is a recognized high‐risk factor. Early diagnosis and treatment can reduce morbidity in affected individuals, and raising societal awareness about consanguinity can help alleviate the disease's burden in populations where this practice is prevalent.

## Linked entities

- **Diseases:** Papillon–Lefèvre syndrome (MONDO:0009490), Nail–Patella Syndrome (MONDO:0008061)

## Full-text entities

- **Diseases:** Papillon-Lefevre Syndrome (MESH:D010214), Nail-Patella Syndrome (MESH:D009261)

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11997255/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC11997255/full.md

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Source: https://tomesphere.com/paper/PMC11997255