# Oncological and Functional Outcomes After Minimally Invasive Surgery for Mid and Low Rectal Adenocarcinoma: A Review

**Authors:** Antonio Costanzo, Lorenzo Vescovi, Valentina Rampulla, Michela Caprioli, Michele Marini, Andrea Rigamonti, Daniele Passannanti, Valentina Crisafulli, Antonio Floridi

PMC · DOI: 10.7759/cureus.82238 · Cureus · 2025-04-14

## TL;DR

This review examines the effectiveness and outcomes of minimally invasive surgery for treating rectal cancer, focusing on cancer control and patient recovery.

## Contribution

The study provides updated evidence on oncological and functional outcomes of minimally invasive rectal cancer surgery.

## Key findings

- Minimally invasive surgery achieves high rates of complete mesorectum and clear resection margins.
- Local recurrence rates are low, with overall and disease-free survival rates showing favorable outcomes.
- Functional disorders such as urinary and sexual issues remain common post-surgery.

## Abstract

In this study, we analyze the oncological and functional outcomes after minimally invasive surgery (laparoscopic and robotic) for mid and low rectal adenocarcinoma. This is a narrative review of articles published from January 2019 to December 2024 in which we analyzed the rate of short-term oncological outcomes (quality of surgical samples), long-term oncological outcomes (recurrence rate, overall survival, and disease-free survival), and functional disorders (urinary, sexual, and bowel function) after minimally invasive surgery.

The rates of complete mesorectum are 67.7%-92.8%, the rate of free circumferential resection margin is 94%-98.2%, and the rate of free distal resection margin is 99.4%-100%. The local recurrence rate is 2.3%-7.3%, the overall survival rate is 80%-95.6%, and the disease-free survival rate is 70%-86.4%. The rate of urinary disorders is 25%-26.5%, sexual disorders are 35%-80%, and bowel disorders are 17%-44.6%.

This review demonstrates that minimally invasive surgery yields favorable oncological and functional outcomes. The continuous evolution in robotic surgery will increasingly lead to interesting implications for rectal surgery, thanks to less surgical trauma and better intraoperative visualization of nerves.

## Linked entities

- **Diseases:** rectal adenocarcinoma (MONDO:0002169)

## Full-text entities

- **Diseases:** urinary disorders (MESH:D014570), Rectal Adenocarcinoma (MESH:D000230), , sexual, and bowel function (MESH:D012778), trauma (MESH:D014947), sexual disorders (MESH:D012734)

## Full text

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## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC11996004/full.md

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Source: https://tomesphere.com/paper/PMC11996004