# Acquired partial lipodystrophy (Barraquer-Simons syndrome) with both-side axillary breasts: A case report

**Authors:** Mohammad Al-Jawad, Lina Mawaldi, Nada Mawaldi, Mariam Krimsty, Silva Ishkanian

PMC · DOI: 10.1016/j.ijscr.2025.111202 · International Journal of Surgery Case Reports · 2025-03-25

## TL;DR

A 34-year-old woman with acquired lipodystrophy and axillary breasts highlights the importance of early diagnosis and multidisciplinary care.

## Contribution

This case report presents a rare manifestation of acquired lipodystrophy with bilateral axillary breasts.

## Key findings

- The patient showed significant facial changes and abnormal fat distribution over five years.
- Surgical excision revealed accessory breast tissue and low hemoglobin levels.
- The case underscores the need for increased awareness and timely diagnosis of lipodystrophy.

## Abstract

Lipodystrophies are conditions characterized by a loss of subcutaneous fat, which can be congenital or acquired, and present in various patterns of fat distribution. Accurate diagnosis is essential for identifying comorbidities and ensuring appropriate multidisciplinary care and targeted treatments.

A 34-year-old female experienced significant facial changes and increased abdominal fat over five years. She had lumps under her armpits discharging white fluid, with clinical findings of low hemoglobin and accessory breast tissue, which was surgically excised.

Acquired generalized lipodystrophy is often overlooked, with over 250 documented cases. It typically presents in adolescence and involves symmetrical fat loss, with potential associations to autoimmune diseases and unique features in this case.

This case emphasizes the complexities of acquired lipodystrophy, especially regarding accessory breast tissue. It highlights the need for thorough evaluations and increased awareness among healthcare providers for timely diagnosis and management.

•A 34-year-old woman presented with significant facial changes and abnormal fat distribution, indicative of acquired generalized lipodystrophy.•She also exhibited accessory breast tissue.•This case emphasizes timely diagnosis of acquired lipodystrophy for better patient outcomes.

A 34-year-old woman presented with significant facial changes and abnormal fat distribution, indicative of acquired generalized lipodystrophy.

She also exhibited accessory breast tissue.

This case emphasizes timely diagnosis of acquired lipodystrophy for better patient outcomes.

## Linked entities

- **Diseases:** acquired lipodystrophy (MONDO:0020089), acquired generalized lipodystrophy (MONDO:0019193)

## Full-text entities

- **Diseases:** Acquired partial lipodystrophy (MESH:C562448), Lipodystrophies (MESH:D008060), autoimmune diseases (MESH:D001327), fat (MESH:D004620)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11995093/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11995093/full.md

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Source: https://tomesphere.com/paper/PMC11995093