# Assessment of photobiomodulation in response to the microcirculation in arteriovenous fistula for hemodialysis patient

## TL;DR

This study explores how photobiomodulation affects blood flow in arteriovenous fistulas of hemodialysis patients, finding better results in younger patients.

## Contribution

The study identifies age and dialysis duration as key factors influencing the effectiveness of photobiomodulation on AVF microcirculation.

## Key findings

- Younger patients (<65 years) showed a 2.31% increase in average velocity and 1.37% in flux after PBM.
- The 830 nm laser had a cumulative effect lasting at least 10 minutes, increasing velocity and flux in younger patients.
- Patients with shorter dialysis duration (<6 years) showed increased AVF velocity and flux after PBM.

## Abstract

Management of blood flow in arteriovenous fistula (AVF) is a critical clinical issue for hemodialysis (HD) patients.

To determine the effect of microcirculation of AVF in HD patients with photobiomodulation (PBM).

Twenty HD patients were enrolled in this study. PBM was used to radiate the palm of HD patients at a total dose of 126 J, and the microcirculatory analysis in AVF was investigated.

Among the patients <65 years old, there is an increase of 2.31% and 1.37% in the average velocity and flux in AVF, respectively. This increase is higher than those observed in patients aged >65 years old. Additionally, the cumulative effect of the 830 nm laser was observed for at least 10 min, resulting in continuous increases of 3.16% in velocity and 1.59% in flux for HD patients <65 years old. On the contrary, the average velocity and flux in AVF increased in patients who had undergone HD for <6 years.

In this study, the age and the duration of HD treatment are the two factors that influence microcirculation in HD patients with PBM. The results suggest that PBM could be used to improve the average velocity and flux in AVF, particularly for younger patients with shorter HD treatment durations.