# Relationship between dental erosion and asthma medication in children: a systematic review

**Authors:** André Alexis Díaz Quevedo, Diana Guadalupe Anaya Rubina, Carol Magaly Cárdenas Flores

PMC · DOI: 10.21142/2523-2754-1301-2025-233 · Revista Científica Odontológica · 2025-03-03

## TL;DR

This study reviews the relationship between asthma medications and dental erosion in children, finding no clear link.

## Contribution

The study provides a systematic review clarifying the ambiguous association between asthma medication and dental erosion in children.

## Key findings

- Some studies show higher dental erosion in children using asthma medications.
- Other studies report higher erosion in healthy children compared to those with asthma.
- Asthma medications are not a determining factor for dental erosion in children.

## Abstract

Dental erosion is an alteration that affects the integrity of teeth, which has several aetiologies. It is mentioned that asthma medications may be an etiologic factor; however, studies fail to clarify the possible association between these variables in children with asthma. Therefore, the purpose of this study will be to determine the relationship between dental erosion and asthma medication consumption in paediatric patients.

A systematic research was performed in databases such as MEDLINE (PubMed), Scopus, Web of Science, Scielo, Cochrane Library, Embase, LILACS and gray literature (Open Gray). Two researchers independently selected the articles according to the population, exposure, outcome, study design (PEOS) question using the Rayyan program. Newcastle-Ottawa scale was used to assess the risk of bias.

Six articles were included from 120 selected articles. The studies by Bairappan, Domenzain and Arafa studies show a higher prevalence of dental erosion in children with asthma medication as opposed to healthy children, whereas the studies by Dugmore and Rock, Alazmah and Rezende report a higher prevalence of erosive lesions in healthy children.

Asthma medications are not a determining factor for the occurrence of erosive lesions in the teeth of paediatric patients with this systemic condition.

## Linked entities

- **Diseases:** asthma (MONDO:0004979)

## Full-text entities

- **Diseases:** Asthma (MESH:D001249), Dental erosion (MESH:D014077)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC11994101/full.md

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Source: https://tomesphere.com/paper/PMC11994101