# Advanced CT angiography in detecting rare arterio-venous malformations: Addressing diagnostic challenges in obscure gastrointestinal bleeding

**Authors:** Swathi Tapaswi Kanna, Kaushik Rajavel, Shoa Nayyer, Pritika Gnanasekaran, Priyadarshini Ramesh, Anshuman Kumar Panda

PMC · DOI: 10.6026/9732063002001917 · Bioinformation · 2024-12-31

## TL;DR

Advanced CT angiography improves detection of rare blood vessel issues causing hard-to-find gastrointestinal bleeding.

## Contribution

Demonstrates CTA's superior sensitivity in diagnosing AVM-related obscure gastrointestinal bleeding.

## Key findings

- CTA identified AVMs in 12% of cases missed by standard endoscopy.
- CTA guided successful surgical control of bleeding in 95% of identified cases.
- CTA showed 92% sensitivity, significantly higher than other imaging methods.

## Abstract

Gastrointestinal bleeding is a common clinical issue, but obscure gastrointestinal bleeding (OGIB) presents significant diagnostic
challenges, especially when caused by arteriovenous malformations (AVMs). This study explored the role of advanced CT angiography (CTA)
in diagnosing and managing AVM-related OGIB in 100 patients. CTA identified AVMs in 12% of cases where standard endoscopy failed
(p < 0.001) and guided successful surgical control of bleeding in 95% of these cases. The sensitivity of CTA (92%) was significantly
higher compared to other imaging modalities (68%; p = 0.002), particularly for small or inaccessible lesions. These findings underscore
CTA's crucial role in improving diagnostic accuracy and enabling targeted therapeutic interventions for challenging cases of OGIB.

## Full-text entities

- **Diseases:** AVMs (MESH:D001165), arterio-venous malformations (MESH:D001159), AVM (MESH:D002538), bleeding (MESH:D006470), Gastrointestinal bleeding (MESH:D006471)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC11993390/full.md

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Source: https://tomesphere.com/paper/PMC11993390