# Effect of amniotic over collagen membrane and buccal fat pad in treating oral sub-mucous fibrosis

## TL;DR

This study compares three treatments for oral submucous fibrosis and finds amniotic membrane to be the most effective.

## Contribution

The study introduces a novel comparison of amniotic membrane against collagen membrane and buccal fat pad for OSMF treatment.

## Key findings

- Amniotic membrane grafts reduced discomfort more effectively than other methods.
- Mouth opening improved significantly with amniotic membrane treatment.
- Epithelisation was faster with amniotic membrane compared to collagen or buccal fat pad.

## Abstract

Oral submucous fibrosis (OSMF) is a chronic condition that involves any portion of the oral cavity and causes restricted mouth
opening due to increasing sub mucosal fibrosis. Various surgical treatment approaches have been used to correct the OSMF. Therefore, it
is of interest to compare the efficiency of amniotic membrane, collagen membrane and buccal fat pad in OSMF patients. Hence, a total 30
patient's diagnosed with OSMF were alienated equally into 3 groups based on treatment method; Group I: buccal pad of fat (BPF), Group
II: mucosal defect with amniotic membrane (AM) and Group III-xenogenous collagen membrane (CM). Results show that AM grafts are advisable
alternative for oral tissue restoration than buccal fat pad flaps and collagen membranes in terms of discomfort reduction, mouth opening
improvement and epithelisation.