# Postpartum Hemorrhage-Induced Acute Kidney Injury Following Obstetric Hysterectomy: A Case Report

**Authors:** Anna Thanasa, Efthymia Thanasa, Emmanouil M Xydias, Evangelos Kamaretsos, Gerasimos Kontogeorgis, Ioannis Paraoulakis, Apostolos C Ziogas, Ioannis Thanasas

PMC · DOI: 10.7759/cureus.80516 · Cureus · 2025-03-13

## TL;DR

A woman developed kidney failure after heavy bleeding following childbirth, requiring surgery and dialysis to recover.

## Contribution

This case highlights postpartum hemorrhage as a rare cause of acute kidney injury following vaginal delivery.

## Key findings

- Postpartum hemorrhage led to acute kidney injury requiring hemodialysis.
- Obstetric hysterectomy was performed to control unmanageable bleeding.
- Renal function was fully restored after six days of dialysis.

## Abstract

Pregnancy-related acute kidney injury (AKI) is rare, with hemorrhage and sepsis being its most common causes when it occurs. A 27-year-old multiparous woman presented to our Emergency Department at 37 weeks of gestation at the end of the second stage of labor. Vaginal delivery was completed without complications, however, immediately postpartum, inadequate uterine contraction led to hemodynamic instability. Conservative measures failed to control the hemorrhage, leading to the decision to perform an obstetric hysterectomy to restore stability. The surgical procedure was successful, however, progressive renal dysfunction with rising creatinine levels occurred postoperatively, prompting the initiation of hemodialysis sessions, which continued for six days until the full restoration of kidney function. This report describes the occurrence of AKI as a result of postpartum hemorrhage following vaginal delivery and outlines its key risk factors, in addition to diagnosis and treatment options. Proper understanding of these factors can significantly contribute to ensuring maternal health and optimizing perinatal outcomes.

## Linked entities

- **Diseases:** acute kidney injury (MONDO:0002492)

## Full-text entities

- **Diseases:** AKI (MESH:D058186), sepsis (MESH:D018805), renal dysfunction (MESH:D007674), Hemorrhage (MESH:D006470)
- **Chemicals:** creatinine (MESH:D003404)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC11993245/full.md

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Source: https://tomesphere.com/paper/PMC11993245