# A case of bloodstream infection caused by Neisseria gonorrhoeae

**Authors:** Danhui Kong, Yue Qiu, Limin Zou, Qi Zhang, Wenjun Zhou, Jie Yang

PMC · DOI: 10.1515/biol-2022-1017 · 2025-04-10

## TL;DR

A rare case of bloodstream infection caused by Neisseria gonorrhoeae was diagnosed and successfully treated with ceftriaxone.

## Contribution

This case highlights the rarity and diagnostic challenges of N. gonorrhoeae bloodstream infections.

## Key findings

- N. gonorrhoeae was identified in a blood culture using mass spectrometry.
- The patient recovered after treatment with ceftriaxone based on drug sensitivity tests.
- The case emphasizes the need for timely testing and collaboration between clinical and microbiology teams.

## Abstract

Neisseria gonorrhoeae is fastidious, visual etiological evidence is extremely difficult to obtain, and positive results from blood cultures are even rarer. A 51-year-old female patient was admitted to our hospital for 3 days with fever, and polyarticular pain was diagnosed as infectious fever by a series of examinations, but the pathogen could not be determined. N. gonorrhoeae was identified by blood culture and mass spectrometry. Combined with the drug sensitivity test results, ceftriaxone was given and she recovered. This case is extremely rare, underlining the importance of standardized timely testing and collaboration between clinical and microbiology laboratories.

## Linked entities

- **Chemicals:** ceftriaxone (PubChem CID 5479530)
- **Species:** Neisseria gonorrhoeae (taxon 485)

## Full-text entities

- **Diseases:** fever (MESH:D005334), polyarticular pain (MESH:D010146), bloodstream infection (MESH:D018805)
- **Chemicals:** ceftriaxone (MESH:D002443)
- **Species:** Neisseria gonorrhoeae (species) [taxon 485], Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11992621/full.md

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Source: https://tomesphere.com/paper/PMC11992621