# Carpometacarpal Joint Arthroplasty in a Patient With Concomitant Von Willebrand Disease: A Case Report

**Authors:** Oles Petrovych, Jakub Florek, Filip Georgiew, Adam Bębenek

PMC · DOI: 10.7759/cureus.80501 · 2025-03-12

## TL;DR

A patient with Von Willebrand disease successfully underwent thumb joint surgery with careful blood management to avoid complications.

## Contribution

This case report highlights effective surgical and hematological management for CMC joint osteoarthritis in a patient with VWD type I.

## Key findings

- Bilateral CMC joint arthroplasty was successfully performed in a patient with VWD type I.
- Perioperative hematological management effectively prevented postoperative complications.
- The patient experienced improved thumb function and reduced pain following surgery.

## Abstract

Thumb carpometacarpal (CMC) joint osteoarthritis is characterized by severe pain, reduced grip strength, and restricted thumb mobility. This condition is among the most prevalent forms of arthrosis, significantly impacting patients' daily activities and overall quality of life. Managing patients with coagulation disorders presents a particular challenge, as they are at increased risk for postoperative bleeding, infectious complications, and the potential need for revision surgery. Von Willebrand disease (VWD) type I, a disorder caused by a deficiency of Von Willebrand factor (VWF), can lead to prolonged blood clotting times. This case report demonstrates the successful management of bilateral CMC joint osteoarthritis in a patient with VWD type I using arthroplasty, emphasizing the importance of perioperative hematological management to prevent complications.

## Linked entities

- **Proteins:** VWF (von Willebrand factor)
- **Diseases:** Von Willebrand disease (MONDO:0019565), osteoarthritis (MONDO:0005178)

## Full-text entities

- **Diseases:** infectious complications (MESH:D003141), pain (MESH:D010146), restricted thumb mobility (MESH:D014086), Von Willebrand Disease (MESH:D014842), bleeding (MESH:D006470), CMC joint (MESH:D007592), Thumb carpometacarpal (CMC) joint osteoarthritis (MESH:D010003), coagulation disorders (MESH:D001778), VWD type I (MESH:D056725), VWF (MESH:C531844)
- **Chemicals:** Carpometacarpal (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11992503/full.md

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Source: https://tomesphere.com/paper/PMC11992503