Fifteen-Year Follow-Up: Treatment of Recurrent Mandibular Giant Cell Lesion—From Resection to Rehabilitation

TL;DR

A 28-year-old woman's long-term treatment of a recurrent jaw lesion led to successful restoration of her jawbone and dental function over 15 years.

Contribution

This case report demonstrates a multidisciplinary approach for managing recurrent central giant cell granuloma with long-term success.

Findings

Alveolar distraction osteogenesis and autogenous bone grafting effectively restored mandibular integrity.

Dental implants placed in 2012 remained stable with healthy tissues at the 15-year follow-up.

Multidisciplinary treatment enabled functional and aesthetic restoration after extensive lesion management.

Abstract

Aim: This case report details the long-term management of a recurrent central giant cell granuloma (CGCG) in the anterior mandibular arch of a 28-year-old female.

Case Report: Following initial surgical resection in 2007, which resulted in a significant bony defect, a multidisciplinary approach was employed to restore mandibular integrity and function. In 2009, alveolar distraction osteogenesis was performed using a DePuy Synthes alveolar distractor. Subsequently, in 2011, autogenous onlay bone grafting was carried out to optimize the alveolar ridge contour. Four Neodent CM implants were placed in 2012, followed by prosthetic rehabilitation. The 15-year follow-up in 2024 revealed excellent outcomes, with stable peri-implant tissues, maintained bone levels, and a fully functional prosthesis. This case highlights the efficacy of combining advanced surgical techniques, including distraction osteogenesis and autogenous bone grafting, in managing complex CGCG cases.

Results and Conclusion: The successful long-term outcome underscores the importance of a comprehensive treatment approach and regular follow-up in addressing the challenges posed by aggressive and recurrent CGCGs. This report provides valuable insights into the potential for fully functional and aesthetic restoration following extensive CGCG treatment, emphasizing the benefits of a well-coordinated, multidisciplinary approach in maxillofacial reconstruction.

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