# A New Computational Method for Detecting Leak Flow and Tidal Volume Waveforms During Spontaneous or Mandatory Breathing Assisted with Nasopharyngeal Ventilation

**Authors:** Francesco Montecchia, Paola Papoff

PMC · DOI: 10.3390/s25072022 · 2025-03-24

## TL;DR

This paper presents a new computational method to accurately measure breathing during nasopharyngeal ventilation by accounting for air leaks.

## Contribution

The novel contribution is a real-time computational model for tidal volume measurement that addresses leak flow in NPV.

## Key findings

- The model's tidal volume measurements are comparable to the gold standard pneumotachograph.
- The method accounts for leak flow, improving accuracy in NPV scenarios.

## Abstract

Nasopharyngeal ventilation (NPV) is a common technique used to support breathing, particularly when a patient’s respiration is inadequate, such as under sedation. It involves delivering oxygen through an endotracheal tube positioned above the glottis. Accurate tidal volume measurement is crucial for anesthesiologists, with the gold standard being a pneumotachograph. However, due to leakage from the mouth or mask, this method has limitations when applied to NPV. This study introduces a computational model that calculates respiratory flow in real time by accounting for leak flow. Results show that tidal volume measurements using this method are comparable to the gold standard, assuming the model’s assumptions hold true.

## Full-text entities

- **Chemicals:** oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11991569/full.md

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Source: https://tomesphere.com/paper/PMC11991569