# Cymodocea nodosa, a Promising Seagrass of Nutraceutical Interest: Overview of Phytochemical Constituents and Potential Therapeutic Uses

**Authors:** Marinella De Leo, Lidia Ciccone, Virginia Menicagli, Elena Balestri, Alessandra Braca, Paola Nieri, Lara Testai

PMC · DOI: 10.3390/nu17071236 · Nutrients · 2025-04-01

## TL;DR

Cymodocea nodosa is a seagrass with promising health benefits due to its bioactive compounds, which may help manage metabolic disorders and act as antioxidants.

## Contribution

This paper reviews the phytochemical composition and therapeutic potential of Cymodocea nodosa, highlighting its underexplored nutraceutical value.

## Key findings

- Cymodocea nodosa contains bioactive compounds like fatty acids, flavonoids, and polysaccharides.
- Extracts from C. nodosa show potential for managing metabolic disorders and providing antioxidant effects.
- Despite its ecological importance, comprehensive chemical studies on C. nodosa remain limited.

## Abstract

Background/Objectives: Seagrasses are marine angiosperms capable of completing their life cycle in water; they have been used as food source and biomass for producing fertilizer, but their potential nutritional and health-promoting properties have been largely overlooked. Cymodocea nodosa (Ucria) Ascherson (family Cymodoceaceae) is emerging as one of the most interesting seagrass species due to its content in health promoting substances. Methods: In this review article, a revision of the literature on phytochemical constituents and the main potential therapeutic uses of C. nodosa was carried out. Results: Despite the growing interest in C. nodosa for its key ecological role and for being a potential source of bioactive compounds, comprehensive chemical studies about its composition are still limited. Compounds reported as C. nodosa constituents include fatty acids, phytosterols, polysaccharides, phenolic acids, hydroxycinnamic acids, flavonoid glycosides, terpenoids, and diarylheptanoids. As concerns potential therapeutic uses, C. nodosa extract, both polyphenolic and polysaccharidic, might be useful for the management of metabolic disorders, which is currently the most documented in addition to the antioxidant action. Conclusions: Cymodocea nodosa emerges as one of the most promising seagrass species as a source of bioactive compounds and for its potential in maintaining health status.

## Linked entities

- **Species:** Cymodocea nodosa (taxon 55448)

## Full-text entities

- **Diseases:** metabolic disorders (MESH:D008659)
- **Species:** Cymodocea nodosa (species) [taxon 55448]

## Full text

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## Figures

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## References

77 references — full list in the complete paper: https://tomesphere.com/paper/PMC11990611/full.md

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Source: https://tomesphere.com/paper/PMC11990611